La maladie de Parkinson au Canada (serveur d'exploration)

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In vitro and in vivo effects within the coronary sinus of nonarcing an arcing shocks using a new system of low-energy DC ablation

Identifieur interne : 004823 ( Main/Exploration ); précédent : 004822; suivant : 004824

In vitro and in vivo effects within the coronary sinus of nonarcing an arcing shocks using a new system of low-energy DC ablation

Auteurs : R. Lemery ; TACK KI LEUNG ; E. Lavellee ; A. Girard ; M. Takajic ; D. Roy ; M. Montpetit

Source :

RBID : Pascal:91-0387302

Descripteurs français

English descriptors

Abstract

This system includes 1) a low-energy ablation power supply with a brief time-constant capacitive discharge that delivers up to 40 J and 3,000 V and 2) a low-energy ablation catheter with a contoured distal electrode. We performed in vitro and in vivo studies of this new system and compared arcing shocks with nonarcing shocks. Ablations were peprformed using unipolar distal shocks (D) and unipolar shocks to both electrodes made electrically common (P-D). In vitro studies were done in a large tank filled with physiological saline while recording voltage, current, and pressure. High-speed cinematography (32,000 frames/sec) of shocks of 10-40 J permitted detailed analysis of the vapor globe. Anodal shocks of less than 20 J showed no arcing or only minimal vapor globe formation. For D and P-D anodal shocks of 40 J, the diameters of the vapor globe were 31 and 22 mm, respectively, corresponding to pressure recordings of 11 and 4.9 atm. The pressure rise lasted less than 50 μsec. In vivo studies involved 18 dogs that received nonarcing shocks (one to six shocks of 15 J) and 18 dogs that received arcing shocks (one to three shocks of 40 J)


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Le document en format XML

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<term>Ablation</term>
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<term>Animals</term>
<term>Arrhythmia</term>
<term>Arrhythmias, Cardiac (surgery)</term>
<term>Cardiac Tamponade (prevention & control)</term>
<term>Cardiovascular disease</term>
<term>Catheter</term>
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<term>Coronary sinus</term>
<term>Dog</term>
<term>Dogs</term>
<term>Electric energy</term>
<term>Electrocoagulation (methods)</term>
<term>Excitability disorder</term>
<term>Experimental study</term>
<term>Exploration</term>
<term>Female</term>
<term>Heart Conduction System (surgery)</term>
<term>Heart Rupture (prevention & control)</term>
<term>Male</term>
<term>Models, Cardiovascular</term>
<term>Models, Structural</term>
<term>Pathology</term>
<term>Treatment</term>
<term>Wolff Parkinson White syndrome</term>
<term>Wolff-Parkinson-White Syndrome (surgery)</term>
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<term>Electrocoagulation</term>
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<term>Cardiac Tamponade</term>
<term>Heart Rupture</term>
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<term>Arrhythmias, Cardiac</term>
<term>Coronary Vessels</term>
<term>Heart Conduction System</term>
<term>Wolff-Parkinson-White Syndrome</term>
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<term>Dogs</term>
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<term>Male</term>
<term>Models, Cardiovascular</term>
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<term>Energie électrique</term>
<term>Wolff Parkinson White syndrome</term>
<term>Trouble conduction</term>
<term>Trouble excitabilité</term>
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<term>Traitement</term>
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<div type="abstract" xml:lang="en">This system includes 1) a low-energy ablation power supply with a brief time-constant capacitive discharge that delivers up to 40 J and 3,000 V and 2) a low-energy ablation catheter with a contoured distal electrode. We performed in vitro and in vivo studies of this new system and compared arcing shocks with nonarcing shocks. Ablations were peprformed using unipolar distal shocks (D) and unipolar shocks to both electrodes made electrically common (P-D). In vitro studies were done in a large tank filled with physiological saline while recording voltage, current, and pressure. High-speed cinematography (32,000 frames/sec) of shocks of 10-40 J permitted detailed analysis of the vapor globe. Anodal shocks of less than 20 J showed no arcing or only minimal vapor globe formation. For D and P-D anodal shocks of 40 J, the diameters of the vapor globe were 31 and 22 mm, respectively, corresponding to pressure recordings of 11 and 4.9 atm. The pressure rise lasted less than 50 μsec. In vivo studies involved 18 dogs that received nonarcing shocks (one to six shocks of 15 J) and 18 dogs that received arcing shocks (one to three shocks of 40 J)</div>
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